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Psophocarpus tetragonolobus lectin II (PTL II, WBA II), Biotinylated
B-1405
| isolated from winged bean |
| PTL II is an acidic dimeric glycoprotein with a molecular weight of about 54,000. Subunits can be dissociated in the absence of reducing agents and migrate in SDS-PAGE as a single band. The isoelectric point of this lectin is about pH 5.5. |
| Like PTL I, this lectin binds preferentially to galactosides, with N-acetylgalactosamine being the most inhibitory monosaccharide. However, in contrast to PTL I, this lectin prefers the beta anomeric configuration. PTL II shows a high affinity toward blood group H structures and the T-antigen. In general, though, PTL II has lower affinities for inhibiting sugars than does PTL I. PTL I and PTL II also differ in their erythrocyte agglutinating properties. Tissue staining results indicate preference for some vascular elements with overall lighter staining than obtained with PTL I. |
| Inhibiting Sugar: 100 mM N-acetylgalactosamine |
MSDS !
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2 mg
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