| The ImmPRESS™ polymerized reporter enzyme staining system is based on a new method of polymerizing enzymes and attaching these polymers to antibodies. The novel approach employed to form enzyme "micropolymers" avoids the intrinsic shortcomings of using large dextrans or other macromolecules as backbones. Attaching a unique "micropolymer" with a high density of very active enzyme to a secondary antibody generates a reagent that overcomes steric interference and provides enhanced accessibility to its target. The result is outstanding sensitivity and signal intensity. |
| Another feature of the ImmPRESS™ reagents is low background staining. Elimination of a large backbone allows better diffusion of the reagents to the target sites and a reduction in non-specific binding. The ImmPRESS™ Anti-Mouse Ig, the ImmPRESS™ Anti-Rabbit Ig, and ImmPRESS™ Anti-Goat Ig reagents are composed of our ultra-pure affinity-purified secondary antibodies coupled with a unique "micropolymer" of a very active form of peroxidase. ImmPRESS™ Universal antibody reagent is a mixture of ImmPRESS™ anti-rabbit Ig and anti-mouse Ig reagents. ImmPRESS™ reagents contain no biotin or avidin. |
| The ImmPRESS reagents are supplied prediluted in a convenient dropper bottle format. No mixing or titering of the ImmPRESS reagents is necessary to obtain optimal tissue section staining. The ready-to-use reagents along with fewer steps in the staining procedure should save time without sacrificing intensity or compromising background quality. |
| ImmPRESS™ Reagent kits consist of 50 ml of 2.5% normal horse blocking serum and 50 ml of the ready-to-use ImmPRESS™ Reagent. |