| The ImmPRESS™ polymerized reporter enzyme staining system is based on a new method of polymerizing enzymes and attaching these polymers to antibodies. The novel approach employed to form enzyme “micro-polymers” avoids the intrinsic shortcomings of using large dextrans or other macromolecules as backbones. Attaching a unique “micropolymer” with a high density of very active enzyme to a secondary antibody generates a reagent that overcomes steric interference and provides enhanced accessibility to its target. The result is outstanding sensitivity and signal intensity. |
| Another feature of the ImmPRESS™ reagents is low background staining. Elimination of a large backbone allows better diffusion of the reagents to the target sites and a reduction in non-specific binding. The ImmPRESS™ Anti-Mouse Ig, the ImmPRESS™ Anti-Rabbit Ig, and ImmPRESS™ Anti-Goat Ig reagents are composed of our ultra-pure affinity-purified secondary antibodies coupled with a unique "micropolymer" of a very active form of peroxidase. ImmPRESS™ Universal antibody reagent is a mixture of ImmPRESS™ anti-rabbit Ig and anti-mouse Ig reagents. ImmPRESS™ reagents contain no biotin or avidin. |
| The ImmPRESS™ reagents are supplied prediluted in a convenient dropper bottle format. No mixing or titering of the ImmPRESS™ reagents is necessary to obtain optimal tissue section staining. The ready-to-use reagents along with fewer steps in the staining procedure saves time without sacrificing intensity or compromising background quality. |
| ImmPRESS™ Reagent kits consist of 50 ml of 2.5% normal horse blocking serum and 50 ml of the ready-to-use ImmPRESS™ Reagent. |