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Jacalin, Agarose bound
AL-1153-10
| isolated from Artocarpus integrifolia (Jackfruit) seeds |
| Jacalin is a lectin composed of four subunits, two of approximately 10,000 daltons and two of 16,000 daltons each. This 50,000 dalton glycoprotein appears to bind only O-glycosidically linked oligosaccharides, preferring the structure galactosyl (b-1,3) N-acetylgalactosamine. This structure (the so-called “T-antigen”) is the oligosaccharide to which peanut agglutinin binds. However, unlike PNA, Jacalin will bind this structure even in a mono- or disialylated form. This lectin has been used to purify human IgA, since no other human immunoglobulin class binds Jacalin (references available upon request). The specificity of this lectin also affords the opportunity to localize or isolate glycoproteins with O-glycosidically linked oligosaccharide side chains. |
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Inhibiting/Eluting Sugar: 800 mM galactose or 100 mM melibiose
4 mg lectin/ml gel |
MSDS !
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10 ml
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